The correct answer is C) the printing press.
Johann Gutenberg's great contribution to the world was the printed press.
Johann Gutenberg (1398-1468) was a German publisher who invented the modern print press as we know it. With this new technology, books and newspapers could be printed in series, spreading information and knowledge in new forms. Johann Fust was the businessman that help Gutenberg with the money to develop the new machine. Without a doubt, the print press revolutionized the world at that time, facilitating the production of books and allowing more people to access to the printed material.
The other options of the question were A) the formulation of the Vaccinations. B) the extraction of paper from wood. D) the system of preserving meat.