First establish how many choices we have at each position:
1. "First five letters of the alphabet" --> 5 possibilities
2. "with no repeats" --> 4 possibilities (5 minus whatever was in spot 1) 
3. "digits 0 through 9" --> 10 possibilities 
4. "with repeats possible" --> 10 possibilities 
5. "with repeats possible" --> 10 possibilities 
Then we can calculate the total number of permutations by multiplying the the number of possibilities for each slot one after another:
