Question

: A dose of 750 mg of acetaminophen is administered to a patient. a blood sample is drawn two hours after the dose is administered. the concentration of acetaminophen is measured as 8 mcg/ml. acetaminophen has a volume of distribution of 51 l. how many milligrams of drug remain in the body 2 hours after the dose is administered? (answer must be numeric; no units or commas.)

Answer 1

To solve this problem, we can calculate for the milligrams of remaining acetaminophen by multiplying the volume with the concentration.

Remaining acetaminophen after 2 hours = Concentration after 2 hours * Volume

Where, concentration = 8 mcg / mL = 8 cg / L

volume = 51 L

Remaining acetaminophen after 2 hours = (8 cg / L) * (51 L) = 408 cg

ANSWER: 408