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Endocrine disrupters: are only active in very large doses or exposures only affect the reproductive capability of females affect the reproduction of fishes, birds, reptiles and mammals only affect the reproduction of humans have been conclusively linked with human health problems

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The correct answer would be the last option. Endocrine disrupters have been conclusively linked with human health problems. These are substances that would interfere with the endocrine functions at a specific dose. Examples are CFC, mercury, CO2 and ozone.  
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User IRon
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