Question

Estimates are that p53 is mutated in 50% of all human cancers. if the gene that encodes p53 is mutated such that p53 is non-functional, what processes would be affected? check all that apply.

Answer 1

if these are the choices:

The ability to halt the cell cycle in response to DNA damage.

The ability to halt the cell cycle in response to the chromosomes not properly aligning on the metaphase plate.

The ability to repair DNA damage.

The ability to activate Cdks.

The ability to stimulate cell death processes if the cell is irreparably damaged.

MY ANSWERS ARE:

The ability to repair DNA damage.

The ability to halt the cell cycle in response to DNA damage.

The ability to stimulate cell death processes if the cell is irreparably damaged.