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A mutation in a dna strand is least likely to affect the cell when the mutation:

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User FiqSky
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A mutation is least likely to affect a cell when the mutation reverses the order of bases in a DNA strand.
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User Jonatascsilva
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A mutation is least likely to affect a cell when the mutation is reverses the order of bases in a DNA strand. when the total number of bases in a DNA sequence remain the same. Replaces a base with its complementary base and produces a codon which codes for the same amino acid as the original codon.

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User Blakev
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