Question

Which type of mutation always creates a stop codon

Answer 1

Nonsense mutation always creates a stop condon

Answer 2

The correct answer is - nonsense mutation.

Explanation:

A nonsense mutation is a mutation that took place due to the substitution or change in a single base pair that was the code for a specific amino acid to the stop codon. The premature stop codon ends in the non-functional shorter polypeptide chain and protein.

Beta thalassemia causes due to the beta-globin protein in which no production or some production of the beta-thalassemia because of short protein due to the nonsense mutation.

Thus, the correct answer is - nonsense mutation.