Question

Classical hemophilia, or hemophilia A, is a genetic disorder in which blood fails to clot. In one family, males are shown to carry and express the defective allele in every other generation, while females seem unaffected. Based on the information given it could be concluded that hemophilia is ___________________.

Answer 1

is a genetic disorder in which blood fails to clot.

Answer 2

The correct answer would be X-linked recessive disorder.

It is an X-linked recessive disorder due to which it is more common in males as compared to females.

Males carry only one X chromosome due to which presence of the single mutant allele is enough to produce the phenotype.

In contrast, the females carry two X chromosomes due to which they require two copies of mutated allele. Thus, the chances of a female to express a disease is less.