Question

Disassembly of the nuclear envelope ________________. select one:

a. causes the inner nuclear membrane to separate from the outer nuclear membrane.
b. results in the conversion of the nuclear envelope into protein-free membrane vesicles.
c. is triggered by the phosphorylation of integrins.

Answer 1

Disassembly of the nuclear envelope must occur for kinetochore microtubules to form in animal cells. This disassembly of nuclear envelope is triggered by the cyclin-dependent kinase at the onset of mitosis. The reassembly is mediated by multiple interactions of the INM proteins with chromatin. Dephosphorylation of INM proteins at late anaphase/telophase is required for nuclear envelope reassembly.