A benzoyl peroxide agent
Benzoyl peroxide is a topical agent that has both antibacterial and comedolytic properties. It is the topical agent most effective in reducing the P. acnes population.
-Bacterial resistance does not develop to benzoyl peroxide. The irritant effect of the drug also causes vasodilation and increased blood flow, which may hasten resolution of the inflammatory lesions.
- Although Accutane, low-dose tetracycline, and Retin-A are often used to treat severe acne, these drugs should not be given to those who are pregnant because they can affect the development of the fetus.