Question

T cell-target cell interactions induce specialized tc cells to produce ________ that kill virus-infected target cells.

Answer 1

T-cells target cell interactions induce specialized Tc cells to produce perforins that kill virus infected target cells. The perforins are pores forming cytolytic protein found in the granules of cytotoxic T lymphocytes and the NK cells. After the process of degranulation, perforin binds to the target cell's plasma membrane, and oligomerises in a calcium ion dependent manner to form pores on the target cell.

Answer 2

The answer is granzymes. are serine proteases which trigger the apoptotic cascade in target cells. Apoptotic enzymes activated by granzymes can also destroy viruses or other cytoplasmic pathogens in the target cells so that the pathogens cannot infect nearby cells. Dead target cells are rapidly ingested by macrophages. The Tc cells also produce perforin pores to allow granzymes to enter the target cell.