Question

What would happen if the kinase that adds the inhibitory phosphate to cdk were defective? see section 12.3 (page 264) . view available hint(s) what would happen if the kinase that adds the inhibitory phosphate to cdk were defective? see section 12.3 (page 264) . the onset of m phase would be delayed. cdk concentrations would spike. mpf levels would become abnormally high. m phase would begin prematurely. submit?

Answer 1

Th answer is ‘the onset of m phase would be delayed’. Cdks are kinases, enzymes that phosphorylate (attach phosphate groups to) specific target proteins. The attached phosphate group acts like a switch, making the target protein more or less active. Cdks must also be phosphorylated on a particular site in order to be active, and may also be negatively regulated by phosphorylation of other sites.