Question

Which domain of the insulin precursor protein is affected by each of the four snps? terms may be used once, more than once, or not at all?

Answer 1

The domain at which the amino acid with single nucleotide polymorphism (SNP) is located will be affected by the SNP.

- Valine (Val) 42 Glycine (Gly): B chain domain

- Alanine (Ala) 74 Threonine (Thr): C peptide domain

- Arginine (Arg) 55 Proline (Pro): Dibasic site domain

- Tyrosine (Tyr) 103-stop: A chain domain