Answer:
Option 4 - 84 
Explanation:
Given : Permutations of the first 9 letters of the alphabet taking 6 letters at a time.
To find : The number of permutation?
Solution : 
According to question we apply combination to find the number of permutations of the first 9 letters of the alphabet taking 6 letters at a time as order doesn't matter.
The combination is given by,

Here, n=9 and r=6

 
 
 
 
Therefore, The number of permutations of the first 9 letters of the alphabet taking 6 letters at a time is 84.
So, Option 4 is correct.