Answer:
- pain 
- delayed growth 
- frequent infections
Step-by-step explanation:
Sickle cell anemia is a genetic and hereditary disease, prevalent in blacks, but may also manifest in whites. It is characterized by a change in red blood cells, which lose their round and elastic shape, take on the appearance of a sickle (hence the sickle cell name) and harden, making it difficult for blood to pass through small vessels and, consequently, tissue oxygenation. 
The most common symptoms are: 
- Severe pain caused by blockage of blood flow and lack of oxygen in tissues; 
- Joint pains; 
- Intense fatigue; 
- Pallor and jaundice; 
- Delayed growth; 
- Leg sores; 
- Tendency to infections; 
- Gallstones; 
- Neurological, cardiovascular, pulmonary and renal problems; 
- Priapism