Answer:
The word that establishes a relationship in the sentence
"Despite our best efforts as parents, we will always make mistakes in raising our children."
Is: B) Despite.
Step-by-step explanation:
The reason here is because of the meaning of despite. That means that the secondary idea of the sentence is not going to be affected by the first one. In other words that one can exist along with the other, that there is no exception and they should not be separated. In other words, the word is saying these two things can go together there is no need to separate them.