Answer:
 “conocer” and  “saber” are the two principal meanings of the verb “to know” in Spanish.
 
Below are their usage in sentences:
Conocer 
- It is used when we have had some experience with a known thing or a known person . 
For example: Yo conozco esa forma de mirar 
I know that way of looking
-It is used to indicate that you have a relationship with a person. 
For example: Ana conoce a Juan desde que eran niños
Ana knows Juan since they were children
-It is also used to say that we have been or visited a place. 
For example: No conozco París
I do not know Paris
-It may also mean "to meet" a place, a thing or a person (for the first time). 
For example: Ellos se conocieron aquella primavera en Japón
They met that spring in Japan
Saber 
-It is used to indicate knowledge of a fact. 
For example: Ella sabe dónde está mi casa
She knows where my house is
-It is used when we talk about knowing skills (also learned skills) or to express the ability to do something, writing the verb in the following form: 
saber+ verb in infinitive . 
For excample: Yo sé manejar muy bien
I know to drive very well