The simplified form of the difference ...
... (5.9×10¹) - (2.8×10⁴)
is ....
... 59 - 28,000 = -27941
... = -2.7941×10⁴
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For the problem given here, no answer choice is correct.
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Comment on the problem
When none of the choices comes even close, I like to recommend you ask your teacher to show you how to work this problem. In most cases, the teacher will recognize the error in the question or answer choices.