Question

What happens when the substrate molecule binds at the active site of the enzyme

Answer 1

When an enzyme binds its substrate, it forms an enzyme-substrate complex. This complex lowers the activation energy of the reaction and promotes its rapid progression by providing certain ions or chemical groups that actually form covalent bonds with molecules as a necessary step of the reaction process. Hope this helps.

Answer 2

the substrate molecule becomes stressed, which allows the reaction to occur.