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Which river was used as a major trade route for the Midwestern United States?

Which river was used as a major trade route for the Midwestern United States?
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Which river was used as a major trade route for the Midwestern United States?

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User Nick Kline
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1 Answer

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When looking at the Midwestern part of the United States, I found the Missouri River. I hope this helps
answered
User Serge Nikitin
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