Question

Nonpolar amino acid residues are typically found in the interior of globular proteins like chymotrypsin (fig. 3.8d). Which chemical force is most directly responsible?

Answer 1

The correct answer is hydrophobic interactions.

The hydrophobic interactions are interactions between nonpolar substances to aggregate in an aqueous solution and to segregate from water molecules. The hydrophobic interactions are essential for the protein folding in which the hydrophobic chains of a protein aggregate into the core of the protein with water molecules around it.