Question

Dorothy has been suffering from epileptic seizures for the past four years. in the context of neurotransmitter functioning, her seizures can be best attributed to the

Answer 1

In the context of neurotransmitter functioning her seizures can best be attributed to the "overstimulation caused by Glutamate".

Overstimulation of glutamate receptors causes neurodegeneration and neuronal harm through a procedure called excitotoxicity. Unnecessary glutamate, or excitotoxins following up on a similar glutamate receptors, overactivate glutamate receptors (particularly NMDARs), causing large amounts of calcium particles (Ca2+) to inundation into the postsynaptic cell.

Glutamate excitotoxicity activated by overstimulation of glutamate receptors likewise adds to intracellular oxidative pressure.