Option B) “owned 100 million acres and many practiced settled farming” is the correct one as their main source of economic input was agriculture. These tribes were very well organized in their political, economic, religious and social aspects. These important communities´ inhabitants were mainly farmers.
Option A) Is incorrect as The Five Civilized Tribes were the Cherokee, Chickasaw, Creek, Choctaw and Seminole.
Option C) is incorrect as the tribes were located in the Southeast.
Option D) is incorrect as they did not start their own university but after the European colonization, these tribes were considered to be “civilized” as they “assimilated” some of the European cultural traits (clothing, religion, language)