Question

Why don't some mutations to a DNA sequence have a significant effect on pheonotypic expression? (2 points) A mutation may cause a change that codes for the same amino acid. The transcription machinery can skip over the mutation in some cases. Proteins are replicated so often that some mutations are not important. A mutation may affect a DNA sequence but not affect resulting mRNA.

Answer 1

The first one: A mutation may cause a change that codes for the same amino acid. It is not possible (or likely) that the transcription will skip over the mutation. Mutations, especially large frameshifts, are important. It does not matter how much proteins are replicated. A mutation in the DNA sequence will affect the mRNA.