asked 6.1k views
2 votes
I propose to design a new drug which will act as an inhibitor for an enzyme. If I have used all current information about the mechanism of this enzyme to design this inhibitor and I carefully engineer it with similar chemical properties of the transition state, what type of inhibitor am I attempting to engineer and how will I know if I have succeeded?

asked
User Dervish
by
8.8k points

1 Answer

1 vote
A competitive inhibitor, collect kinetic data both in the presence and absence of inhibitor and watch for a change in KM. Hope I’ve helped ;)
answered
User Leon Fedotov
by
7.7k points
Welcome to Qamnty — a place to ask, share, and grow together. Join our community and get real answers from real people.