Question

In sporadic cases of retinoblastoma, only two gene mutations are thought to be necessary in the same cell for a tumor to develop. This happens when an organism inherits a mutant allele and a wild-type allele forms the parents. When the wild-type allele is mutated, resulting in tumorigenesis, this process is called, ________.a. metastasizingb. attenuationc. gain of heterozygosityd. loss of heterozygositye. recombination

Answer 1

D) loss of heterozygosity

Step-by-step explanation:

In sporadic cases of retinoblastoma, only two gene mutations are thought to be necessary in the same cell for a tumor to develop. This happens when an organism inherits a mutant allele and a wild-type allele forms the parents. When the wild-type allele is mutated, resulting in tumorigenesis, this process is called loss of heterozygosity.