The Akkadan Empire of Mesopotamia controlled the largest amount of territory.
Step-by-step explanation:
The Akkadan Empire was the first ancient empire of the Mesopotamian civilization. This empire exercised influence across Mesopotamia and even sent military expeditions down south. The Akkadan Empire reached its political peak during the 24th and 22nd centuries BC.
The empire was able to make several conquests of territories thereby gaining more and more territory. the founder of the Akkadan Empire was Sargon who led several conquests in a successful manner and rules ably.