Question

if the carriers are not affected by the trait what percentage of offspring in the second generation are affected

Answer 1

The percentage of offfspring depends on whether both or only one of the parents is a carrier.

For example, Allele t represents a disease. Allele T is the dominant allele.

T t

T TT Tt

t Tt tt

When both of the parents are carriers, then there will be a 25% chance that the offsprings will be affected.