Question

A point mutation occurs in a sex cell of an adult rabbit. The gene affected by

the mutation is responsible for proteins that build heart muscles. Which
describes the most likely effect of this mutation?

Answer 1

This point mutation in the sex cell of the rabbit by the heart muscle building protein would cause death of the rabbit.

Step-by-step explanation:

Adult transgenic rabbits are used to represent human race to experiment different diseases and syndromes of humans. One such experiment is conducted to identify the cardiovascular disease and cardiac rhythm syndrome, known as LQT syndrome.

This disease leads to the cardiac death of patient the human mutants- KCNQ1, KCNH2, which causes this syndrome were represented by rabbits. This gene is overexpressed in the rabbit’s cardiomyocytes through the heavy chain of β-myosin. The LQT2 affected rabbits showed more prolongation of QT and increase in death.