Question

Excess acetyl CoA that accumulates during fat breakdown is modified in the liver by which of the following pathways? Excess acetyl CoA that accumulates during fat breakdown is modified in the liver by which of the following pathways? ketogenesis lipolysis lipogenesis beta oxidation

Answer 1

Ketogenesis

Step-by-step explanation:

As acetyl CoA accumulates in liver cells, the process called ketogenesis begins. It includes condensation of two molecules of acetyl CoA into acetoacetic acid. This reaction releases a large amount of CoA which cannot diffuse out of cells. Some acetoacetic acid is converted into beta-hydroxybutyric acid and acetone. The acetoacetic acid, beta-hydroxybutyric acid and acetone are collectively known as ketone bodies and the process of their formation is called ketogenesis.