Question

"The RNA polymerase II C-terminal domain (CTD) consists of multiple repeats of the heptapeptide sequence YSPTSPS, with the number of repeats varying among organisms. Hyperphosphorylation of the CTD is a key step in the transition of the enzyme complex from the initiation to the elongation stage. What does the term "hyperphosphorylation" mean in this context?

Answer 1

Multiple copies of the heptapeptide repeat are phosphorylated on some combination of serine, threonine, and tyrosine residues.

Step-by-step explanation: