Question

Students are reviewing the concepts of phenotype and genotype as they apply to hypercholesterolemia. The students demonstrate an understanding by identifying which as characteristic of the genotype of this disease?

Answer 1

The most common cause of this condition arise from mutations in the LDLR gene. The LDLR gene provides the information for cells to make proteins called a low-density lipoprotein receptor. The risk of high cholesterol in a person is greater because a gene defect (mutation) changes how cholesterol is processed by the body