Answer:
The correct answer will be option-A.
Step-by-step explanation:
Recombineering is a molecular technique based on the recombination mechanism of DNA which is also known as recombination-mediated genetic engineering.
This method is used mainly in bacterial genetics to generate conditional mouse knockout target vector and modifying DNA in Bacterial artificial chromosome.
Since it does not use older methods like restriction enzymes and DNA ligases to combine DNA, therefore, option-A is the correct answer.