Answer:
metabolism has affected the drug.
Step-by-step explanation:
Given this situation, the nurse can conclude that metabolism, also called biotransformation affected the drug indicated to the patient.
Metabolism of a drug, also known as biotransformation, is a process that submits a drug to chemical reactions usually mediated by enzymes that convert it into behaviors different from the originally administered. This metabolism happens mainly in the liver and consists of charging the medication so that when passing through the renal tubes, it is not reabsorbed.