Question

What is the importance of the blood-testis barrier?

A. It prevents spermatids from being released from the seminiferous tubule in an immature state.
B. It ensures that sperm remain isolated from ova until a mature ovum has reached an appropriate fertilization location in the female reproductive tract.
C. It prevents escape of membrane antigens of differentiating sperm through the basal lamina and into the blood, where they would activate the immune system.
D. It forms a continuous barrier between sustentocytes and developing spermatocytes to prevent cross-contamination of genetic material.

Answer 1

C. It prevents escape of membrane antigens of differentiating sperm through the basal lamina and into the blood, where they would activate the immune system.

Step-by-step explanation:

The blood-testis barrier is present in all the animals. It is a barrier formed by a tight junction between the Sertoli cells. It forms compartments which separate fluid environment for successful spermatogenesis. The blood-testis barrier stops sperm antigens from contacting systemic and lymph circulations, preventing an immune response.