Question

Phosphatidylinositol 4,5-bisphosphate (PIP2) can be acted on by different enzymes that get activated by receptor protein tyrosine kinases. Name one of these enzymes, explain what it does to PIP2.

Answer 1

Phosphatidylinositol 4,5-bisphosphate (PIP2) is the small constituent of the plasma membrane. This molecule acts as a an important signalling molecules and helps in the cell communication process.

Phospholipase C gamma is an enzymes that get activated by receptor protein tyrosine kinases on Phosphatidylinositol 4,5-bisphosphate (PIP2). This enzyme cleaves and mediates the PIP2 molecule as a precursors of diacylglycerol and inositol(1,4,5)P3.