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Leptin "resistance" would result in ____________________.

a. decreased satiety
b. decreased appetite
c. lower circulating leptin
d. higher concentrations of ghrelin

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User Curtisp
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1 Answer

3 votes

Answer:

a. decreased satiety

Step-by-step explanation:

Leptin hormone is synthesized and released in the bloodstream by adipocytes. Higher levels of stored triglycerides result in more leptin secreted in the bloodstream. The function of leptin is to target hypothalamus and inhibit food intake.

Leptin suppresses appetite and increases satiety by inhibiting the release of neuropeptide Y from the arcuate nucleus. Leptin resistance is caused by many factors.

For example, leptin resistance occurs when the leptin receptors present in the brain do not function properly and the binding of leptin to the receptors does not inhibit the release of neuropeptide Y. And neuropeptide Y increases appetite and reduces satiety.

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User Erdinc Ay
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