Question

Which of the following HLA haplotypes is strongly associated with rheumatoid arthritis?(A) HLA-B8 (B) HLA-B27 (C) HLA-B51 (D) HLA-DR4 (E) HLA-DRB3

Answer 1

Answer: Option D

Explanation:

The inherited chances of rheumatoid arthritis is associated with the DRB 1 genes which encodes HLA-DR4 and HLA-DR1 molecules (human leukocyte antigen).

Rheumatoid arthritis can be defined as an autoimmune disorder which includes inflammation in joints. Pain and stiffness, swollen joints.

It involves the same joints on both side of the body.

Hence, the correct answer is Option D