The correct answer to this open question is the following.
Immigrants coming to America from Eastern and Southern Europe during the late 19th century were most likely to settle in large cities of the Northwest and the or the Midwest.
These European people had many motives to leave their native countries such as hunger, poverty, religious or political persecution, and the simple idea of looking for a better life for their families. They arrived in the United States at the end of the 1800s and got low paid jobs in factories and manufacture industries in large cities such as New York City. There, they lived in small, crowded places under unhealthy conditions.